Myofascial pain syndrome (MPS), characterized by painful myofascial “trigger points,” is among the most prevalent causes of acute and chronic musculoskeletal pain, affecting 10–15% of patients in general medical clinics and up to 85% of individuals at some point in their lives. Despite its prevalence, the subjective nature of current diagnostic approaches and the lack of objective biomarkers have limited the accuracy of MPS diagnosis and treatment.
This project aims to develop PET and MRI techniques to identify novel imaging biomarkers of myofascial tissue damage and associated inflammatory mediators. By providing objective measures of trigger points and the sources of pain, this research seeks to improve the diagnosis, characterization, and management of MPS.

Project Lead
This work was supported by NIH grant R61EB036126 “Imaging of pain sources in myofascial pain syndrome”.
Researchers at the Center for Biomedical Imaging at NYU Langone Health develop transformative imaging technologies to advance basic science and address unsolved clinical problems.
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