Projects

Cellular Viscosity as a Marker for Alzheimer’s Disease Pathology: A Combined Multiparametric MR Spectroscopy and PET Study

This project investigates intracellular viscosity as a potential early marker of neurodegeneration and Alzheimer’s disease by combining PET imaging, blood-based biomarkers, and an innovative technique called magnetic resonance spectroscopic fingerprinting (MRSF), using data from a well-characterized cohort at NYU’s Alzheimer’s Disease Research Center.

AGING   BRAIN

Open-Source Software Tools for Rapid Radiofrequency Coil Modeling and Simulation in MRI

This project develops open-source, memory-efficient electromagnetic simulation tools using tensor decompositions and optimization techniques to improve RF coil modeling for ultra-high field MRI, enhancing image quality and safety while reducing computational and licensing barriers.

COILS   SIMULATIONS   SOFTWARE

Understanding CSF Clearance in Aging and Alzheimer’s Brain Through Dynamic Sodium MRI

This study uses advanced MRI techniques to investigate how sleep and aging affect cerebrospinal fluid clearance in healthy individuals and Alzheimer’s patients, aiming to understand the glymphatic system’s role in brain health and disease progression.

AGING   BRAIN   X-NUCLEI

GRASP MRI

This project focuses on the ongoing development and clinical translation of GRASP MRI—a fast, motion-robust dynamic imaging method combining golden-angle radial sampling, compressed sensing, and parallel imaging—which has been widely adopted in clinical practice, expanded into advanced variants, and increasingly applied in both diagnostic and therapeutic settings.

BRAIN   RAPID MRI

Imaging of pain sources in myofascial pain syndrome

This project aims to develop PET and MRI techniques to identify novel imaging biomarkers of myofascial tissue damage and associated inflammatory mediators, providing objective measures of trigger points and the sources of pain to improve the diagnosis, characterization, and management of myofascial pain syndrome.

MSK   QUANTITATIVE MRI
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