Projects

Imaging and Therapeutic Targeting of Tissue Crosstalk in the Injured Knee

This project investigates the interplay between inflammation and apoptosis in post-traumatic osteoarthritis (PTOA) using in vitro and in vivo methods to develop therapeutic strategies that target both pathways and prevent disease progression.

MOLECULAR IMAGING   MSK

Breast cancer Intravoxel Incoherent Motion Multisite (BRIMM) Project

The BRIMM project is a multi-site breast cancer study using intravoxel incoherent motion (IVIM) MRI to develop a robust, cross-platform imaging biomarker that noninvasively characterizes the tumor microenvironment and predicts response to neoadjuvant chemotherapy.

BREAST   DIFFUSION MRI

Open-Source Software Tools for Rapid Radiofrequency Coil Modeling and Simulation in MRI

This project develops open-source, memory-efficient electromagnetic simulation tools using tensor decompositions and optimization techniques to improve RF coil modeling for ultra-high field MRI, enhancing image quality and safety while reducing computational and licensing barriers.

COILS   SIMULATIONS   SOFTWARE

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Multi-Scale and Multi-Modality Imaging of Neuropathology in VCID

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

AGING   BRAIN
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