Faculty

Contact Information

Els D. Fieremans, PhD

Associate Professor
In my current research, I focus on validation methods for diffusion MRI including both hardware and numerical phantoms, as well as animal models. I thereby seek to develop and translate new imaging markers for neurodegeneration, as well as body diffusion applications in muscle and the prostate, using advanced biophysical modeling of non-Gaussian and time-dependent diffusion in biological tissue.

Research Projects

Multi-Scale and Multi-Modality Imaging of Neuropathology in VCID

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

AGING   BRAIN

Neuroimaging Core of NYU Langone’s Alzheimer’s Disease Research Center

The neuroimaging core of NYU Langone’s Alzheimer Disease Research Center supports research on Alzheimer’s and related dementias by developing and applying advanced imaging techniques to aid early diagnosis, track disease progression, and inform novel diagnostics and treatments.

AGING   BRAIN

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Brain Microstructure Imaging

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify tissue microstructure in the brain—such as axonal integrity, inflammation, fiber orientation dispersion, axonal diameters, axonal beading, undulations, and water exchange—using diffusion methods and a leading-edge Siemens Connectom.X gradient system.

BRAIN   DIFFUSION MRI