Projects

GRASP MRI

This project focuses on the ongoing development and clinical translation of GRASP MRI—a fast, motion-robust dynamic imaging method combining golden-angle radial sampling, compressed sensing, and parallel imaging—which has been widely adopted in clinical practice, expanded into advanced variants, and increasingly applied in both diagnostic and therapeutic settings.

BRAIN   RAPID MRI

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI

Tissue Microstructure Imaging in the Body

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify microstructural properties in muscle tissue and the prostate using methods for estimating physiological properties, the random permeable barrier model, and diffusion relaxometry acquisitions.

BRAIN   DIFFUSION MRI

In Vivo Insights into Aging-Related Small-Vessel Changes Using USPIO-Enhanced MRI

This project aims to develop an ultra-high-resolution USPIO-enhanced MRI technique to visualize the brain's microvascular architecture, quantify vascular density, and investigate age-related neurovascular changes, potentially advancing the understanding of microvascular aging and its role in neurologic disorders.

AGING   BRAIN

Multi-Scale and Multi-Modality Imaging of Neuropathology in VCID

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

AGING   BRAIN
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