Projects

Neural Underpinning of Cognitive and Behavioral Deficits in Psychotic Spectrum Disorders

This research uses a multi-modal approach to reveal the neural mechanisms underlying psychotic spectrum disorders and to provide objective biomarkers for assessing disease progression and treatment efficacy.

BRAIN   DIFFUSION MRI

Multi-Scale and Multi-Modality Imaging of Neuropathology in VCID

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

AGING   BRAIN

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI

Cellular Viscosity as a Marker for Alzheimer’s Disease Pathology: A Combined Multiparametric MR Spectroscopy and PET Study

This project investigates intracellular viscosity as a potential early marker of neurodegeneration and Alzheimer’s disease by combining PET imaging, blood-based biomarkers, and an innovative technique called magnetic resonance spectroscopic fingerprinting (MRSF), using data from a well-characterized cohort at NYU’s Alzheimer’s Disease Research Center.

AGING   BRAIN

Understanding CSF Clearance in Aging and Alzheimer’s Brain Through Dynamic Sodium MRI

This study uses advanced MRI techniques to investigate how sleep and aging affect cerebrospinal fluid clearance in healthy individuals and Alzheimer’s patients, aiming to understand the glymphatic system’s role in brain health and disease progression.

AGING   BRAIN   X-NUCLEI
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Researchers at the Center for Biomedical Imaging at NYU Langone Health develop transformative imaging technologies to advance basic science and address unsolved clinical problems.

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This content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health, NYU Langone Health, or New York University.