Projects

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI

Multi-Scale and Multi-Modality Imaging of Neuropathology in VCID

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

AGING   BRAIN

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

In Vivo Insights into Aging-Related Small-Vessel Changes Using USPIO-Enhanced MRI

This project aims to develop an ultra-high-resolution USPIO-enhanced MRI technique to visualize the brain's microvascular architecture, quantify vascular density, and investigate age-related neurovascular changes, potentially advancing the understanding of microvascular aging and its role in neurologic disorders.

AGING   BRAIN

Understanding CSF Clearance in Aging and Alzheimer’s Brain Through Dynamic Sodium MRI

This study uses advanced MRI techniques to investigate how sleep and aging affect cerebrospinal fluid clearance in healthy individuals and Alzheimer’s patients, aiming to understand the glymphatic system’s role in brain health and disease progression.

AGING   BRAIN   X-NUCLEI
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