Projects

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Brain Microstructure Imaging

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify tissue microstructure in the brain—such as axonal integrity, inflammation, fiber orientation dispersion, axonal diameters, axonal beading, undulations, and water exchange—using diffusion methods and a leading-edge Siemens Connectom.X gradient system.

BRAIN   DIFFUSION MRI

Neuroimaging Core of NYU Langone’s Alzheimer’s Disease Research Center

The neuroimaging core of NYU Langone’s Alzheimer Disease Research Center supports research on Alzheimer’s and related dementias by developing and applying advanced imaging techniques to aid early diagnosis, track disease progression, and inform novel diagnostics and treatments.

AGING   BRAIN

Tissue Microstructure Imaging in the Body

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify microstructural properties in muscle tissue and the prostate using methods for estimating physiological properties, the random permeable barrier model, and diffusion relaxometry acquisitions.

BRAIN   DIFFUSION MRI

In Vivo Insights into Aging-Related Small-Vessel Changes Using USPIO-Enhanced MRI

This project aims to develop an ultra-high-resolution USPIO-enhanced MRI technique to visualize the brain's microvascular architecture, quantify vascular density, and investigate age-related neurovascular changes, potentially advancing the understanding of microvascular aging and its role in neurologic disorders.

AGING   BRAIN
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