Projects

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI

Improving the Efficacy of Ultra-Low-Field MRI Using AI

This project aims to develop AI methods to improve the image quality of ultra-low-field MRI to enhance the mobility, accessibility, and efficiency of MRI in clinical radiology and neuroscientific research.

AI   BRAIN

Brain Microstructure Imaging

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify tissue microstructure in the brain—such as axonal integrity, inflammation, fiber orientation dispersion, axonal diameters, axonal beading, undulations, and water exchange—using diffusion methods and a leading-edge Siemens Connectom.X gradient system.

BRAIN   DIFFUSION MRI   MICROSTRUCTURE

Biomarkers of Abnormal Brain Aging

This research investigates early mechanisms of abnormal brain aging and validates early biomarkers to identify pre-symptomatic stages before clinical symptoms appear.

AGING   BRAIN
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