Projects

Advanced Diffusion MRI in Renal Cancer: Oncologic Control and Renal Functional Reserve

This project investigates REFMAP, an advanced diffusion MRI approach combining IVIM and DTI, to noninvasively diagnose kidney tumors, estimate glomerular filtration rate, and predict renal function outcomes following surgery.

DIFFUSION MRI   KIDNEYS

Breast cancer Intravoxel Incoherent Motion Multisite (BRIMM) Project

The BRIMM project is a multi-site breast cancer study using intravoxel incoherent motion (IVIM) MRI to develop a robust, cross-platform imaging biomarker that noninvasively characterizes the tumor microenvironment and predicts response to neoadjuvant chemotherapy.

BREAST   DIFFUSION MRI

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Brain Microstructure Imaging

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify tissue microstructure in the brain—such as axonal integrity, inflammation, fiber orientation dispersion, axonal diameters, axonal beading, undulations, and water exchange—using diffusion methods and a leading-edge Siemens Connectom.X gradient system.

BRAIN   DIFFUSION MRI