Projects

Tissue Microstructure Imaging in the Body

This project develops and validates biophysical models of diffusion and nuclear magnetic resonance relaxation to quantify microstructural properties in muscle tissue and the prostate using methods for estimating physiological properties, the random permeable barrier model, and diffusion relaxometry acquisitions.

BRAIN   DIFFUSION MRI   MICROSTRUCTURE

Breast cancer Intravoxel Incoherent Motion Multisite (BRIMM) Project

The BRIMM project is a multi-site breast cancer study using intravoxel incoherent motion (IVIM) MRI to develop a robust, cross-platform imaging biomarker that noninvasively characterizes the tumor microenvironment and predicts response to neoadjuvant chemotherapy.

BREAST   DIFFUSION MRI

Neural Underpinning of Cognitive and Behavioral Deficits in Psychotic Spectrum Disorders

This research uses a multi-modal approach to reveal the neural mechanisms underlying psychotic spectrum disorders and to provide objective biomarkers for assessing disease progression and treatment efficacy.

BRAIN   DIFFUSION MRI

Unpacking the Importance of the Structural Injuries in Mild Traumatic Brain Injury

This project uses advanced diffusion MRI techniques and novel analysis methods to identify imaging biomarkers of brain changes and cognitive outcomes in patients with mild traumatic brain injury, aiming to improve diagnosis, prognosis, and treatment planning.

BRAIN   DIFFUSION MRI

Fingerprinting-Based Neuronal Fiber Identification in Brain Surgery

This study aims to advance understanding of neurodegeneration in VCID by developing postmortem MRI protocols, computational tools, and multi-modal atlases, standardizing MRI and histology methods, and creating extensive imaging and biomaterial resources to support research in AD, ADRD, and related pathologies.

BRAIN   DIFFUSION MRI
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